成果發表
學術期刊論文
2024年
- Dachshund Homolog 1: Unveiling Its Potential Role in Megakaryopoiesis and
Bacillus anthracis Lethal Toxin Induced Thrombocytopenia
Guan-Ling Lin, Hsin-Hou Chang, Wei-Ting Lin, Yu-Shan Liou, Yi-Ling Lai, Min-Hua Hsieh, Po-Kong Chen, Chi-Yuan Liao, Chi-Chih Tsai, Tso-Fu Wang, Sung-Chao Chu, Jyh-Hwa Kau, Hsin-Hsien Huang, Hui-Ling Hsu and Der-Shan Sun
Int. J. Mol. Sci. 2024, 25(6), 3102; https://doi.org/10.3390/ijms25063102
2023年
- The Role of Activating Transcription Factor 3 in Metformin’s Alleviation of Gastrointestinal Injury Induced by Restraint Stress in Mice
Bijaya Siwakoti, Te-Sheng Lien, You-Yen Lin, Subhashree Pethaperumal, Shih-Che Hung, Der-Shan Sun, Ching-Feng Cheng andHsin-Hou Chang
Int. J. Mol. Sci. 2023, 24(13), 10995; https://doi.org/10.3390/ijms241310995 - Simulation of Hemorrhage Pathogenesis in Mice through Dual Stimulation with Dengue Envelope Protein Domain III-Coated Nanoparticles and Antiplatelet Antibody
Te-Sheng Lien, Der-Shan Sun, Wen-Sheng Wu and Hsin-Hou Chang
Int. J. Mol. Sci. 2023, 24(11), 9270; https://doi.org/10.3390/ijms24119270 - Restraint Stress-Induced Immunosuppression Is Associated with Concurrent Macrophage Pyroptosis Cell Death in Mice
Chi-Cheng Li, Rina Munalisa, Hsuan-Yun Lee, Te-Sheng Lien, Hao Chan, Shih-Che Hung, Der-Shan Sun , Ching-Feng Cheng and Hsin-Hou Chang
Int. J. Mol. Sci. 2023, 24(16), 12877; https://doi.org/10.3390/ijms241612877 - Restraint stress‑associated gastrointestinal injury and implications from the Evans blue‑fed restraint stress mouse model
Der‑Shan Sun, Te‑Sheng Lien, Hsin‑Hou Chang
Tzu Chi Medical Journal 36(1):p 23-29, Jan–Mar 2024. DOI: 10.4103/tcmj.tcmj_101_23 - Protective effects of compound M01 on retinal ganglion cells in experimental anterior ischemic optic neuropathy by inhibiting TXNIP/NLRP3 inflammasome pathway
Jia-Ying Chien, Jhih-Wei Ciou, Yun Yen, Shun-Ping Huang
Biomed Pharmacother. 2023 Dec 31:169:115861. doi: 10.1016/j.biopha.2023.115861. - Platelet-derived circulating soluble P-selectin is sufficient to induce hematopoietic stem cell mobilization
Tso-Fu Wang, Yu-Shan Liou, Shang-Hsien Yang, Guan-Ling Lin, Ya-Wen Chiang, Te-Sheng Lien , Chi-Cheng Li, Jen-Hung Wang, Hsin-Hou Chang, Der-Shan Sun
Stem Cell Res Ther. 2023 Oct 20;14(1):300. doi: 10.1186/s13287-023-03527-w. - The Neuroprotective Effects of Flavonoid Fisetin against Corticosterone-Induced Cell Death through Modulation of ERK, p38, and PI3K/Akt/FOXO3a-Dependent Pathways in PC12 Cells
Pei-Rong Chang ,Je-Wen Liou ,Pei-Yi Chen ,Wan-Yun Gao ,Chia-Ling Wu ,Ming-Jiuan Wu and Jui-Hung Yen
Pharmaceutics 2023, 15(10), 2376; https://doi.org/10.3390/pharmaceutics15102376 - Pinostrobin modulates FOXO3 expression, nuclear localization, and exerts antileukemic effects in AML cells and zebrafish xenografts
Pei-Yi Chen , Ching-Yen Lin , Chia-Ling Wu , Pei Ying Keak , Je-Wen Liou , Wan-Yun Gao , Liang-In Lin , Jui-Hung Yen
Chemico-Biological Interactions 2023;110729. doi: 10.1016/j.cbi.2023.110729 - Comparison, Analysis, and Molecular Dynamics Simulations of Structures of a Viral Protein Modeled Using Various Computational Tools
Hemalatha Mani ,Chun-Chun Chang ,Hao-Jen Hsu ,Chin-Hao Yang ,Jui-Hung Yen and Je-Wen Liou
Bioengineering 2023, 10, 1004. https://doi.org/ 10.3390/bioengineering10091004 - Cell Cycle Regulation by NF-YC in Drosophila Eye Imaginal Disc: Implications for Synchronization in the Non-Proliferative Region
Anthony Avellino, Chen-Huan Peng, and Ming-Der Lin
Int. J. Mol. Sci. 2023, 24(15), 12203. https://doi.org/10.3390/ijms241512203 - Drosophila Phosphatase of Regenerating Liver Is Critical for Photoreceptor Cell Polarity and Survival during Retinal Development
Shu-Fen Chen, Hsin-Lun Hsien, Ting-Fang Wang and Ming-Der Lin
Int. J. Mol. Sci. 2023, 24, 11501. https://doi.org/ 10.3390/ijms241411501
2022年
- Effect of Size and Concentration of Copper Nanoparticles on the Antimicrobial Activity in Escherichia coli through Multiple Mechanisms
Meng-Jiun Lai, Yue-Wern Huang, Hsuan-Chun Chen, Li-I Tsao, Chih-Fang Chang Chien,Bhaskar Singh and Betty Revon Liu
Nanomaterials 2022, 12(21), 3715; https://doi.org/10.3390/nano12213715 - Behavioral and Synaptic Phenotypes of Female Prdx6−/− Micel
Tanita Pairojana, Sarayut Phasuk, Pavithra Suresh, Ingrid Y Liu
Antioxidants (Basel). 2022 Jun 19;11(6):1201. doi: 10.3390/antiox11061201. - Attenuation of HECT-E3 ligase expression rescued memory deficits in 3xTg-AD mice
Pavithra Suresh, Sureka Jasmin, Yun Yen, Hao-Jen Hsu, Peeraporn Varinthra, Tanita Pairojana, Chien-Chang Chen and Ingrid Y. Liu
Front. Aging Neurosci., 29 July 2022 Volume 14 - 2022; https://doi.org/10.3389/fnagi.2022.916904 - The Effects of Lycium chinense, Cuscuta chinensis, Senna tora, Ophiopogon japonicus, and Dendrobium nobile Decoction on a Dry Eye Mouse Model
Cheng-Chan Yang,Jia-Ying Chien,Yu-Yau Chou,Jhih-Wei Ciou and Shun-Ping Huang
Medicina 2022, 58(8), 1134; https://doi.org/10.3390/medicina58081134 - 5-Demethylnobiletin Inhibits Cell Proliferation, Downregulates ID1 Expression, Modulates the NF-κB/TNF-α Pathway and Exerts Antileukemic Effects in AML Cells
Pei-Yi Chen, Chih-Yang Wang, En-Ci Tsao, Yu-Ting Chen, Ming-Jiuan Wu, Chi-Tang Ho, Jui-Hung Yen
Int J Mol Sci. 2022 Jul 2;23(13):7392. doi: 10.3390/ijms23137392. - Nanodiamond-induced thrombocytopenia in mice involves P-selectin-dependent Nlrp3 inflammasome-mediated platelet aggregation and pyroptosis
Shih-Che Hung, Lu-Chu Ke, Te-Sheng Lien, Hsuan-Shun Huang, Der-Shan Sun Chia-Liang Cheng and Hsin-Hou Chang
Front. Immunol., 04 April 2022. doi:org/10.3389/fimmu.2022.806686 - The Protective Effects of n-Butylidenephthalide on Retinal Ganglion Cells during Ischemic Injury
Yu-Yau Chou ,Jia-Ying Chien ,Jhih-Wei Ciou and Shun-Ping Huang
nt. J. Mol. Sci. 2022, 23(4), 2095. doi:org/10.3390/ijms23042095.
2021年
- Activating Transcription Factor 3 Protects against Restraint Stress-Induced Gastrointestinal Injury in Mice
Dun-Jie Chuang, Subhashree Pethaperumal, Bijaya Siwakoti, Hung-Jen Chien, Ching-Feng Cheng, Shih-Che Hung, Te-Sheng Lien, Der-Shan Sun and Hsin-Hou Chang
Cells. 2021 Dec 14;10(12):3530. doi:10.3390/cells10123530. - Nanosized Particles Assembled by a Recombinant Virus Protein Are Able to Encapsulate Negatively Charged Molecules and Structured RNA
Hemalatha Mani, Yi-Cheng Chen, Yen-Kai Chen, Wei-Lin Liu, Shih-Yen Lo, Shu-Hsuan Lin and Je-Wen Liou
Polymers (Basel). 2021 Mar 11;13(6):858. doi: 10.3390/polym13060858. - Valine-279 Deletion-Mutation on Arginine Vasopressin Receptor 2 Causes Obstruction in G-Protein Binding Site: A Clinical Nephrogenic Diabetes Insipidus Case and Its Sub-Molecular Pathogenic Analysis
Ming-Chun Chen, Yu-Chao Hsiao, Chun-Chun Chang, Sheng-Feng Pan, Chih-Wen Peng, Ya-Tzu Li, Cheng-Der Liu, Je-Wen Liou and Hao-Jen Hsu
Biomedicines. 2021 Mar 15;9(3):301. doi: 10.3390/biomedicines9030301. - Peroxiredoxin 6 Knockout Mice Demonstrate Anxiety Behavior and Attenuated Contextual Fear Memory after Receiving Acute Immobilization Stress
Sarayut Phasuk, Peeraporn Varinthra, Andaman Nitjapol, Korakod Bandasak and Ingrid Y Liuu
Antioxidants (Basel). 2021 Sep 4;10(9):1416. doi: 10.3390/antiox10091416. - Saussurea involucrata (Snow Lotus) ICE1 and ICE2 Orthologues Involved in Regulating Cold Stress Tolerance in Transgenic Arabidopsis
Chia-Ling Wu, Lee-Fong Lin, Hsiao-Chun Hsu, Li-Fen Huang, Chung-Der Hsiao and Ming-Lun Chou
IJMS; 2021/ Oct 7/ 22(19):10850. doi: 10.3390/ijms221910850. - The Effects of Two Nrf2 Activators, Bardoxolone Methyl and Omaveloxolone, on Retinal Ganglion Cell Survival during Ischemic Optic Neuropathy
Jia-Ying Chien,Yu-Yau Chou,Jhih-Wei Ciou,Fang-Yun Liu and Shun-Ping Huang
Antioxidants; 2021, 10(9), 1466; https://doi.org/10.3390/antiox10091466 - Protective Effects of Oroxylin A on Retinal Ganglion Cells in Experimental Model of Anterior Ischemic Optic Neuropathy
Jia-Ying Chien, Shu-Fang Lin, Yu-Yau Chou, Chi-Ying F Huang, Shun-Ping Huang
Antioxidants; 2021 Jun 3;10(6):902. doi: 10.3390/antiox10060902. - AQP0 is a novel surface marker for deciphering abnormal erythropoiesis
Tso-Fu Wang, Guan-Ling Lin, Sung-Chao Chu, Chang-Chin Chen, Yu-Shan Liou, Hsin-Hou Chang, Der-Shan Sun
Stem Cell Res Ther.; 2021 May 6;12(1):274. doi: 10.1186/s13287-021-02343-4. - Lack of the peroxiredoxin 6 gene causes impaired spatial memory and abnormal synaptic plasticity
Sarayut Phasuk, Sureka Jasmin, Tanita Pairojana, Hsueh-Kai Chang, Kai-Chi Liang & Ingrid Y. Liu
Molecular Brain; 2021 Apr 19; 14(1):72. doi: 10.1186/s13041-021-00779-6. - Tanshinone IIA Downregulates Lipogenic Gene Expression and Attenuates Lipid Accumulation through the Modulation of LxRα/SREBP1 Pathway in HepG2 Cells
Wan-Yun Gao, Pei-Yi Chen, Hao-Jen Hsu, Ching-Yen Lin, Ming-Jiuan Wu, Jui-Hung Yen
Biomedicines; 2021 Mar 23;9(3):326. doi: 10.3390/biomedicines9030326. - Dengue Virus Envelope Protein Domain III Induces Nlrp3 Inflammasome-Dependent NETosis-Mediated Inflammation in Mice
Te-Sheng Lien, Der-Shan Sun, Shih-Che Hung, Wen-Sheng Wu, Hsin-Hou Chang
Front Immunol.; 2021 Mar 17;12:618577. doi: 10.3389/fimmu.2021.618577. eCollection 2021. - Enhanced contextual fear memory in peroxiredoxin 6 knockout mice is associated with hyperactivation of MAPK signaling pathway.
Sarayut Phasuk, Tanita Pairojana, Pavithra Suresh, Chee-Hing Yang, Sittiruk Roytrakul, Shun-Ping Huang, Chien-Chang Chen, Narawut Pakaprot, Supin Chompoopong, Sutisa Nudmamud-Thanoi, Ingrid Y Liu
Molecular Brain; 2021 Feb 25;14(1):42. doi: 10.1186/s13041-021-00754-1. - The 4-(Phenylsulfanyl) butan-2-one Improves Impaired Fear Memory Retrieval and Reduces Excessive Inflammatory Response in Triple Transgenic Alzheimer's Disease Mice.
Peeraporn Varinthra, Kiruthika Ganesan, Shun-Ping Huang, Supin Chompoopong, Chatchakorn Eurtivong, Pavithra Suresh, Zhi-Hong Wen, Ingrid Y Liu
Frontiers in Aging Neuroscience; 2021 Feb 3;13:615079. doi: 10.3389/fnagi.2021.615079. - Exposure to Dengue Envelope Protein Domain III Induces Nlrp3 Inflammasome-Dependent Endothelial Dysfunction and Hemorrhage in Mice
Te-Sheng Lien, Der-Shan Sun, Cheng-Yeu Wu, Hsin-Hou Chang
Front Immunol.; 2021 Feb 25;12:617251. doi: 10.3389/fimmu.2021.617251. eCollection 2021. - PKCδ mediates mitochondrial ROS generation and oxidation of HSP60 to relieve RKIP inhibition on MAPK pathway for HCC progression
Jaya Prakash Mandal, Chiou-Nan Shiue, Yen-Cheng Chen, Ming-Che Lee, Hsueh-Hui Yang, Hsin-Hou Chang, Chi-Tan Hu, Pei-Chen Liao, Lin-Ching Hui, Ren-In You, Wen-Sheng Wu
Free Radic Biol Med.; 2021 Feb 1;163:69-87. doi: 10.1016/j.freeradbiomed.2020.12.003
2020年
- Dissecting the role of a plant-specific Rab5 small GTPase NbRabF1 in Bamboo mosaic virus infection.
Ying-Ping Huang, Pei-Yu Hou, I-Hsuan Chen, Yau-Huei Hsu, Ching-Hsiu Tsai, Chi-Ping Cheng
Journal of Experimental Botany; 2020 Dec 31;71(22):6932-6944. doi: 10.1093/jxb/eraa422. - 4-(Phenylsulfanyl) Butan-2-One Attenuates the Inflammatory Response Induced by Amyloid-β Oligomers in Retinal Pigment Epithelium Cells.
Peeraporn Varinthra, Shun-Ping Huang, Supin Chompoopong, Zhi-Hong Wen, Ingrid Y Liu
Marine Drugs; 2020 Dec 23;19(1):1. doi: 10.3390/md19010001. - Visible-Light-Responsive Antibacterial Property of Boron-Doped Titania Films
Ming-Show Wong, Man-Ting Sun, Der-Shan Sun and Hsin-Hou Chang
Catalysts 2020, 10(11), 1349; https://doi.org/10.3390/catal10111349 - Silver Nanoparticles Protect Skin from Ultraviolet B-Induced Damage in Mice
Yu-Yi Ho, Der-Shan Sun, Hsin-Hou Chang
Int J Mol Sci.; 2020 Sep 25;21(19):7082. doi: 10.3390/ijms21197082. - Drosophila decapping protein 2 modulates the formation of cortical F-actin for germ plasm assembly
Yi-Mei Lee, Po-Hsun Chiang, Jen-Ho Cheng, Wei-Hong Shen, Chao-Han Chen, Mei-Ling Wu, Yi-Lu Tian, Chao-Heng Ni, Ting-Fang Wang, Ming-Der Lin, Tze-Bin Chou
Dev Biol.; 2020 May 1;461(1):96-106. doi: 10.1016/j.ydbio.2020.01.013 - Suppressed humoral immunity is associated with dengue nonstructural protein NS1-elicited anti-death receptor antibody fractions in mice
Chung-Lin Tsai, Der-Shan Sun, Mei-Tzu Su, Te-Sheng Lien, Yen-Hsu Chen, Chun-Yu Lin, Chung-Hao Huang, Chwan-Chuen King, Chen-Ru Li, Tai-Hung Chen, Yu-Hsiang Chiu, Chun-Chi Lu & Hsin-Hou Chang
Scientific Reports; 2020 Apr 14;10(1):6294. doi: 10.1038/s41598-020-62958-0. - Tyrosine kinase inhibitors modulate dendritic cell activity via confining c-Kit signaling and tryptophan metabolism.
Ching-Liang Chu, Yi-Pang Lee, Cheng-Yoong Pang, Huei-Ru Lin, Chang-Shan Chen, Ren-In You
International Immunopharmacology; 2020 Mar 6;82:106357. doi: 10.1016/j.intimp.2020.106357.
- Oogenesis of Hematophagous Midge Forcipomyia taiwana (Diptera: Ceratopogonidae) and Nuage Localization of Vasa in Germline Cells
Szu-Chieh Wang, Yung-Hao Ching, Preethi Krishnaraj, Guan-Yu Chen, Anna Shiny Radhakrishnan, Hsien-Min Lee, Wu-Chun Tu, Ming-Der Lin
Insects; 2020 Feb 5;11(2):106. doi: 10.3390/insects11020106.
2019年
- Intermittent Hypoxia Induces Autophagy to Protect Cardiomyocytes From Endoplasmic Reticulum Stress and Apoptosis
Jui-Chih Chang, Wei-Fen Hu, Wen-Sen Lee, Jian-Hong Lin, Pei-Ching Ting, Huai-Ren Chang, Kun-Ruey Shieh, Tsung-I Chen, Kun-Ta Yang
Front Physiol. 2019 Aug 7;10:995. doi: 10.3389/fphys.2019.00995. eCollection 2019. - Palmitic Acid Methyl Ester Induces G2/M Arrest in Human Bone Marrow-Derived Mesenchymal Stem Cells via the p53/p21 Pathway
Jian Hong Lin, Pei Ching Ting, Wen Sen Lee, Hung Wen Chiu, Chun An Chien, Chin Hung Liu, Li Yi Sun, Kun Ta Yang
Stem Cells Int.; 2019 Dec 1;2019:7606238. doi: 10.1155/2019/7606238. - Intermittent Hypoxia Prevents Myocardial Mitochondrial Ca2+ Overload and Cell Death during Ischemia/Reperfusion:The Role of reactive Oxygen Species
Jui-Chih Chang, Chih-Feng Lien, Wen-Sen Lee, Huai-Ren Chang, Yu-Cheng Hsu, Yu-Po Luo, Jing-Ren Jeng, Jen-Che Hsieh, Kun-Ta Yang
Cells; 2019 Jun 9;8(6):564. doi: 10.3390/cells8060564. - In vivo pro-angiogenic effects of dracorhodin perchlorate in zebrafish embryos: A novel bioactivity evaluation platform for commercial dragon blood samples
Preethi Krishnaraj, Yu Chang, Tsung-Jung Ho, Nai-Chen Lu, Ming-Der Lin, Hao-Ping Chen
Journal of Food and Drug Analysis; 2019 Jan;27(1):259-265. doi: 10.1016/j.jfda.2018.08.005. - Raman spectroscopy on live mouse early embryo while it continues to develop into blastocyst in vitro
Elena Perevedentseva, Alexander Krivokharchenko, Artashes V. Karmenyan, Hsin-Hou Chang & Chia-Liang Cheng
Scientific Reports; 2019 Apr 29;9(1):6636. doi: 10.1038/s41598-019-42958-5.
- Thioacetamide-induced liver damage and thrombocytopenia is associated with induction of antiplatelet autoantibody in mice
You-Yen Lin, Chi-Tan Hu, Der-Shan Sun, Te-Sheng Lien & Hsin-Hou Chang
Scientific Reports; 2019 Nov 25;9(1):17497. doi: 10.1038/s41598-019-53977-7.
2018年
- Different effects of granulocyte colony-stimulating factor and erythropoietin on erythropoiesis
Tzu-Lin Chen, Ya-Wen Chiang, Guan-Ling Lin, Hsin-Hou Chang, Te-Sheng Lien, Min-Hua Sheh, Der-Shan Sun
Stem Cell Res Ther.; 2018 May 2;9(1):119. doi: 10.1186/s13287-018-0877-2.
專利
2020年
- 小動物視覺眼電生理系統_Diagnosys/Celeris System
中華民國專利證書號:I691508
發明人:HUANG, SHUN PING, TSAI, RONG KUNG
專利名稱:用於提供眼部神經保護或用於預防、治療與視網膜神經節細胞死亡相關的眼部疾病或減輕其影響的方法
- 雷射光凝固儀_NIDEK/GYC-500
中華民國專利證書號:I691508
發明人:HUANG, SHUN PING, TSAI, RONG KUNG
專利名稱:用於提供眼部神經保護或用於預防、治療與視網膜神經節細胞死亡相關的眼部疾病或減輕其影響的方法